The European Chemicals Agency (ECHA) has published an assessment of regulatory needs (ARN) concluding that no EU-wide regulatory risk management action is currently needed for a group of 20 acrylate and methacrylate amines, given the information available on them today. However, ECHA added a caveat indicating that some group members, which manifest skin sensitizing properties, may be affected in the future by separate ongoing investigative work into skin sensitizers in consumer mixtures.
BY SCOTT STEPHENS, MPA | JAN 12, 2023 7:40 PM EST
Substance name | EC/List number | CAS number |
Subgroup 1: Secondary/tertiary amines acrylate/methacrylate | ||
2-(diethylamino)ethyl methacrylate | 203-275-7 | 105-16-8 |
2-(dimethylamino) ethyl acrylate | 219-460-0 | 2439-35-2 |
2-dimethylaminoethyl methacrylate | 220-688-8 | 2867-47-2 |
2-tert-butylaminoethyl methacrylate | 223-228-4 | 3775-90-4 |
Subgroup 2: Quaternary amines acrylate/methacrylate | ||
dimethyl[2-[(2-methyl-1- oxoallyl)oxy]ethyl](3- sulphopropyl)ammonium hydroxide | 222-860-8 | 3637-26-1 |
[2-(methacryloyloxy)ethyl]trimethylammonium chloride | 225-733-5 | 5039-78-1 |
[2-(methacryloyloxy)ethyl]trimethylammonium methyl sulphate | 229-995-1 | 6891-44-7 |
[2-(acryloyloxy)ethyl]trimethylammonium methyl sulphate | 236-029-2 | 13106-44-0 |
ethyldimethyl[2- [(2-methyl-1-oxoallyl)oxy]ethyl]ammonium ethyl sulphate | 236-195-6 | 13223-03-5 |
[2-(acryloyloxy)ethyl]trimethylammonium chloride | 256-176-6 | 44992-01-0 |
benzyldimethyl[2-[(1- oxoallyl)oxy]ethyl]ammonium chloride | 256-283-8 | 46830-22-2 |
benzyldimethyl[2 -[(2-methyl-1- oxoallyl)oxy]ethyl] ammonium chloride | 256-288-5 | 46917-07-1 |
3,5,8-Trioxa-4- phosphaundec- 10-en-1- aminium, 4- hydroxy- N,N,N,10- tetramethyl-9- oxo-, inner salt, 4-oxide | 417-560-0 | 67881-98-5 |
Subgroup 3: Ethoxylates/propoxylate acrylate amines | ||
Propylidynetrimethanol, ethoxylated, esters with acrylic acid, reaction products with diethylamine | 500-425-6 | 159034-91-0 |
Glycerol, propoxylated, esters with acrylic acid, reaction products with diethylamine | 500-744-0 | 162492-10-6 |
2-Propenoic acid, (1-methyl-1,2- ethanediyl) bis[oxy(methyl- 2,1-ethanediyl)] ester, reaction products with diethylamine | 601-101-8 | 111497-86-0 |
1-Butanamine, N-butyl-, reaction products with polyethylene- polypropylene glycol ether with trimethylolpropane (3:1) acrylate |
605-658-8
|
173011-06-8 |
ethanamine, N- ethyl-, reaction products with polyethylene- polypropylene glycol ether with trimethylolpropane (3:1) acrylate (>1 <6.5 mol EO and >1 < 6.5 mol PO) |
605-659-3
|
173046-61-2 |
1-Butanamine, N-butyl-, reaction products with polyethylene glycol monoacrylate ether with trimethylolpropane (3:1) |
606-330-7
|
195008-76-5 |
propylidynetrimethanol, ethoxylated, esters with acrylic acid and its reactions products with dibutylamine | 701-363-4 | — |
To contact the author of this analysis, please email Scott Stephens ( [email protected])
To contact the editor of this piece, please email Patricia Iscaro ( [email protected])